Clinical observation on effect of kesuning granule in treating acute onset of chronic bronchitis
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine / Zhongguo Zhong xi yi jie he xue hui, Zhongguo Zhong yi yan jiu yuan zhu ban(2002)
Abstract
Objective To prove the effect of Kesuning Granule (KSNG) in treating chronic bronchitis in exacerbation (Phlegm-Heat syndrome) and objectively evaluate its safety. Methods The double-blinded, double-dummy and randomized controlled method was adopted to observe 120 patients, who were divided into the treated group ( n —60, treated with KSNG 8g, three times a day) and the control group ( n =60, treated with Jinbei Tankeqing Granule (JBTKQ) 7g, three times a day). The therapeutic course for both groups was 6 days. Results In the treated group, the markedly effective rate was 58. 33% and effective rate was 93.33%, while in the control group, they were 51.67% and 91. 67% respectively, no significant difference was found between the two groups. For therapeutic effects on TCM syndromes, the markedly effective rate and effective rate in the treated group was 68. 33% and 93.33% respectively and in the control group, 66.67% and 90.00% respectively, also showed insignificant difference. The effect initiative time was earlier in the treated group than that in the control group significantly ( P <0.05). No adverse effect was found in the observation. Conclusion KSNG shows a definite clinical effect with no obvious toxic-adverse effects.
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Key words
Cerebral Infarction,Effective Rate,Acute Onset,Chronic Bronchitis,Insignificant Difference
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