Optimization of thermosensitive chitosan hydrogels for the sustained delivery of venlafaxine hydrochloride.
International Journal of Pharmaceutics(2013)
Abstract
Delivery of venlafaxine hydrochloride with thermosensitive chitosan hydrogels system: diffusion controlled release and kinetic gelation mechanism is nucleation and growth.
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Key words
Chitosan,Glycerophosphate disodium,Thermosensitive hydrogel,Box–Behnken design,Release mechanism,Venlafaxine
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