Acquired Immune-Deficiency Syndrome With Focal Onset Of Mycobacterium Avium Infection Displaying A Histological/Genetic Pattern Of Disseminated Mycobacteria
INTERNAL MEDICINE(2012)
摘要
A 66-year-old man with human immunodeficiency virus (HIV) infection was admitted for treatment of Pneumocystis pneumonia. Upon admission, a tumor mass adjacent to the thoracic descending aorta was revealed on computed tomography. Histology revealed an exudative granuloma with histiocytes packed with numerous acid-fast bacilli. Mycobacterium avium was isolated from the tissue. A genetic examination of the isolates demonstrated this strain to be located in the cluster consisting of strains that cause systemic infection. The patient's baseline CD4(+) cell count was 9/mu L and the HIV-RNA viral load was 43,800 copies/mL. This case suggests the possibility of a localized onset of disseminated M. avium infection.
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关键词
HIV, disseminated mycobacteriosis, Mycobacterium avium, immune reconstitution inflammatory syndrome
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