Relationship between vertebral artery hypoplasia and posterior circulation stroke in Chinese patients
NEURORADIOLOGY(2012)
Abstract
Introduction Vertebral artery hypoplasia (VAH), which has been found in about 10 % of normal individuals, does not produce symptoms but may be associated with an increased risk of cerebral posterior circulation ischemic (PCI) stroke. The aims of this study were to determine the prevalence of VAH in Chinese patients with cerebral infarction and investigate whether VAH is an independent risk factor for PCI stroke. Methods The medical records of 841 Chinese stroke patients were reviewed retrospectively. All patients underwent either cervical contrast-enhanced magnetic resonance angiography (CE-MRA) or cervical computed tomography angiography (CTA). There is no standard definition of VAH; we defined it as a vertebral artery <2 mm in diameter and the whole artery was slim or absent on CE-MRA or CTA. Univariate and multivariate logistic regression analyses were performed to identify significant independent risk factors for PCI stroke. Results There were 230 patients (27.3 %) diagnosed with PCI stroke and 91 patients diagnosed with VAH (10.8 %). Multivariate logistic regression analysis showed that VAH, male gender, and stenosis of the posterior circulation were independent risk factors for PCI stroke. Conclusions Our results show that VAH is not rare in Chinese patients with stroke and that its presence increases the risk of PCI stroke.
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Key words
Posterior cerebral infarction,Vertebral artery hypoplasia,Magnetic resonance angiography,Computed tomography angiography,Cerebral posterior circulation ischemic stroke
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