Role of beta-defensin-1 polymorphisms in mother-to-child transmission of HIV-1.

Elisabetta Ricci,Sandro Malacrida,Marisa Zanchetta,Marco Montagna,Carlo Giaquinto,Anita De Rossi

Journal of acquired immune deficiency syndromes (1999)（2009）

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摘要

These results demonstrate a significant relationship between genetic variants of beta-defensin-1 gene, viral load, and MTCT of HIV-1, thus supporting a critical role of innate immunity in pediatric HIV-1 infection.

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