The prognostic role of TGF-β signaling pathway in breast cancer patients

E.M. de Kruijf,T.J.A. Dekker,L.J.A.C. Hawinkels,H. Putter,V.T.H.B.M. Smit,J.R. Kroep,P.J.K. Kuppen,C.J.H. van de Velde,P. ten Dijke,R.A.E.M. Tollenaar,W.E. Mesker

Annals of Oncology（2013）

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摘要

Combining TGF-β biomarkers provides prognostic information for patients with stage I-III breast cancer. This can identify patients at increased risk for disease recurrence that might therefore be candidates for additional treatment.

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关键词

breast cancer,prognosis,p-Smad2,smad4,TGF-β receptor I,TGF-β receptor II

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