Intercellular synchronization of diffusively coupled Ca 2+ oscillators

We examine the synchrony in the dynamics of localized [Ca 2 + ] i oscillations among a group of cells exhibiting such complex Ca 2 + oscillations, connected in the form of long chain, via diffusing coupling where cytosolic Ca 2 + and inositol 1,4,5-triphosphate are coupling molecules. Based on our numerical results, we could able to identify three regimes, namely desynchronized, transition and synchronized regimes in the ( T − k e ) (time period-coupling constant) and ( A − k e ) (amplitude-coupling constant) spaces which are supported by phase plots (Δ ϕ verses time) and recurrence plots, respectively. We further show the increase of synchronization among the cells as the number of coupling molecules increases in the ( T − k e ) and ( A − k e ) spaces.