A randomized, double-blind comparison of a clindamycin phosphate/benzoyl peroxide gel formulation and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgaris.
Clinical Therapeutics（2002）
摘要
Background: One approach to suppressing the overgrowth of antibiotic-resistant bacteria is to develop combination products composed of active constituents with complementary but distinct mechanisms of antibacterial action.
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关键词
acne vulgaris,bacterial resistance,benzoyl peroxide,clindamycin,Propionibacterium acnes
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