OX40 signaling favors the induction of T H 9 cells and airway inflammation
NATURE IMMUNOLOGY(2012)
摘要
T H 9 cells secrete copious amounts of IL-9, but how their generation is controlled remains poorly defined. Li and colleagues demonstrate that ligation of the costimulatory receptor OX40 potently generates T H 9 cells in a manner dependent on noncanonical NF-κB signaling.
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nature immunology, science
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