Probing the lactose.GM3 carbohydrate-carbohydrate interaction with glycodendrimers.
ORGANIC LETTERS(2009)
摘要
Multivalent glycoconjugates were prepared using generation-4 PAMAM dendrimers, and their interaction with Langmuir monolayers containing GM3 was investigated. Excessive carbohydrate valency adversely affects the carbohydrate-carbohydrate interaction. The GM3 monolayer selectively interacts with lactose-functionalized dendrimers in the presence of calcium ions.
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