Isolation And Neuroprotective Activities Of Acylated Iridoids From Valeriana Jatamansi
CHEMISTRY & BIODIVERSITY(2012)
摘要
Three new iridoids, jatairidoids AC (13, resp.), have been isolated from the roots of Valeriana jatamansi (V. wallichii). Their structures were elucidated by spectroscopic methods (IR, ESI-MS, HR-ESI-MS, 1D- and 2D-NMR). Compounds 1 and 2 are C(3)-epimers. The three compounds were evaluated for their neuroprotective effects against MPP+-induced neuronal cell death in human dopaminergic neuroblastoma SH-SY5Y cells. All the isolates exhibited moderate neuroprotective effects.
更多查看译文
关键词
Valeriana jatamansi, Iridoids, Jatairidoids A?-?C, Neuroprotective effects
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要