A Preliminary Randomised Controlled Trial Evaluating The Efficacy Of Saline Douching Following Endoscopic Sinus Surgery

Objective: To assess whether saline reduces postoperative signs following endoscopic sinus surgery (ESS).Design: Within subject, single blinded randomised controlled trial.Setting: Single secondary referral centre.Participants: Adults undergoing bilateral ESS for chronic rhinosinusitis or nasal polyposis.Intervention: Saline douching of one side of the nasal cavity, three times per day for 6 weeks.Main outcome measures: Presence of adhesions, polyps, crusting, discharge or oedema under endoscopic examination at 3 weeks and 3 months postoperative.Results: Twenty-three patients were recruited. Attendance was 22 patients at 3 weeks and 17 patients at 3 months. At 3 weeks saline douching significantly improved the presence of discharge (P = 0.046) and non-significantly improved the presence of oedema (P = 0.059) with minimal difference with regard to polyps (P = 0.32) and no difference with adhesions or crusting. At 3 months there was minimal difference with regard to crusting (P = 0.18) and oedema (P = 0.32) and no difference with adhesions, discharge and polyps.Conclusions: Saline douching reduces nasal discharge and may improve oedema during the healing phase following ESS which may represent a possible anti-inflammatory role. No long-term effect was found.