Hortonones A to C, hydroazulenones from the genus Hortonia.
JOURNAL OF NATURAL PRODUCTS(2012)
摘要
The new hexahydroazulenones hortonones A (1) to C (3) were isolated from the leaves of three representative species of the endemic Sri Lankan genus Hortonia that belongs to the family Monimiaceae. Hortonones A (1) and B (2) have the unprecedented rearranged hortonane sesquiterpenoid carbon skeleton, and hortonone C (3) has the unprecedented rearranged and degraded 13-norhortonane skeleton. Hortonone C (3) exhibited in vitro cytotmdcity against human breast cancer MCF-7 cells at 5 mu g/mL.
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