ANTIBIOTICS FROM GLIDING BACTERIA - PRODUCTION, ISOLATION, PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES OF ANGIOLAM-A, A NEW ANTIBIOTIC FROM ANGIOCOCCUS-DISCIFORMIS (MYXOBACTERALES)

Angiolam A, a new lactone-lactam antibiotic, was isolated from the culture broth of the myxobacterium Angiococcus disciformis strain An d30. It was active against a few Gram-positive bacteria and mutant strains of Escherichia coli with increased permeability. It appears to interfere with protein synthesis.