DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

NATURE IMMUNOLOGY（2012）

引用 173|浏览28

暂无评分

摘要

Dock8 deficiency leads to defects in humoral immunity. Geha and colleagues show that Dock88 interacts with MyD88 to bridge TLR9 signaling to the Src-Syk-STAT3 pathway to promote B cell proliferation and differentiation.

查看译文

关键词

Biomedicine,general,Immunology,Infectious Diseases

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要