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New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action

Manuel Tsiang,Gregg S. Jones,Anita Niedziela-Majka,Elaine Kan,Eric B. Lansdon,Wayne Huang,Magdeleine Hung,Dharmaraj Samuel,Nikolai Novikov,Yili Xu,Michael Mitchell,Hongyan Guo,Kerim Babaoglu,Xiaohong Liu,Romas Geleziunas,Roman Sakowicz

Journal of Biological Chemistry（2012）

Cited 152|Views57
Key words
Antiviral Agents,Crystal Structure,Fluorescence Resonance Energy Transfer (FRET),HIV-1,Integrase,Allosteric Inhibitor,Antiviral Mechanism
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