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NEIL1 mRNA splicing variants are expressed in normal mouse organs.

Ryohei Yamamoto,Mizuki Yamamoto, Hiroyuki Kusaka,Hideaki Masatsugu,Satoshi Matsuyama,Tomoko Tajima,Hiroshi Ide,Kihei Kubo

Journal of Radiation Research（2012）

Cited 3|Views13
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Abstract
Oxidized pyrimidines are mainly repaired by base excision repair, which is initiated by damage-specific DNA glycosylases. NEIL1, the mammalian homolog of Escherichia coli endonuclease VIII and a major DNA glycosylase, initiates repair of oxidized pyrimidines. Here, we investigated the expression of two putative variant mouse NEIL1 (mNEIL1) mRNAs—variant 1 ("Neil1 protein" mRNA; BC043297 in the NCB...
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Key words
NEIL1,Glycosylase,BER,Splicing variant,Mouse
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