Operative cholangiography with an antiseptic contrast solution. An experimental study in dogs.

A new antiseptic contrast material, composed of sodium diatrizoate-meglumine diatrizoate and PVP-iodine solutions, was prepared and tested for operative cholangiography. It was tested in vitro, and in vivo in dogs and displayed satisfactory contrast radiologic features, and strong and rapid bactericidal action without detectable side effects. It seems to be promising in reducing the risk of bacterial spread during cholangiography.