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Anaplastic lymphoma kinase in human cancer.

Critical reviews in oncogenesis(2012)

Cited 115|Views5
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Abstract
The anaplastic lymphoma kinase (ALK) receptor tyrosine kinase is now implicated in a wide range of human cancers. Results from recent clinical trials with ALK inhibitors provide promise for patients harboring oncogenic ALK lesions. This review will discuss our current understanding of ALK in human cancer and the implication of recent results for treatment.
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Key words
anaplastic lymphoma,kinase,human cancer
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