Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study of the Oral Γ-Secretase Inhibitor BMS-708163 (avagacestat): Tolerability Profile, Pharmacokinetic Parameters, and Pharmacodynamic Markers.
Clinical therapeutics（2012）
关键词
avagacestat,Alzheimer's disease,A beta(1-40),gamma-secretase inhibitor,pharmacodynamic,pharmacokinetic,tolerability
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