Synthetic polymer nanoparticles conjugated with FimH(A) from E. coli pili to emulate the bacterial mode of epithelial internalization.

Lily Yun Lin,Kristin M Tiemann,Yali Li,Jerome S Pinkner,Jennifer N Walker,Scott J Hultgren,David A Hunstad,Karen L Wooley

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY（2012）

引用 10|浏览6

暂无评分

摘要

Amphiphilic block copolymer nanoparticles are conjugated with uropathogenic Escherichia coli type 1 pilus adhesin FimH(A) through amidation chemistry to enable bladder epithelial cell binding and internalization of the nanoparticles in vitro.

查看译文

关键词

polymers,nanoparticles,particle size,escherichia coli

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要