Study of the Drosophila melanogaster trf2 gene and its protein product
Genetika(2011)
摘要
The Drosophila melanogaster TRF2 protein regulates transcription of several genes. The trf2 gene structure was studied. The gene proved to code for two protein isoforms, a known 75-kDa isoform and a newly identified 175-kDa isoform. The new isoform combines the known isoform sequence with an extended N end containing a coiled-coil motif. The long TRF2 isoform was found to act as a component of a multiprotein complex, including ISWI ATPase as well.
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关键词
Polytene Chromosome,Multiprotein Complex,Immune Staining,TRF2 Protein,Trf2 Gene
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