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α-GalCer通过使供鼠T细胞向Th2极化而减轻急性移植物抗宿主病

刘景华,周凡,窦立萍,王莉莉,王立新,李鲤,于力

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi（2011）

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Abstract
急性移植物抗宿主病(aGVHD)是异基因造血干细胞移植后移植早期的主要并发症和致死原因,因此探索出能够减轻aGVHD的药物和治疗手段具有重要意义.Th1/Th2细胞因子比例失衡在aGVHD发病机制中起主要作用[1-2].
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Key words
th2 polarization,donor,[alpha-galcer,graft-versus-host
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