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Synthesis, SAR and Biological Evaluation of 1,6-Disubstituted-1h-pyrazolo[3,4-d]pyrimidines As Dual Inhibitors of Aurora Kinases and CDK1

Bioorganic & Medicinal Chemistry Letters(2012)

Cited 37|Views17
Key words
Aurora kinase,Cyclin dependent kinase,Cell cycle arrest,Pyrazolopyrimidine,Cytotoxicity
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