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Thiadiazolidinones: a new class of alanine racemase inhibitors with antimicrobial activity against methicillin-resistant Staphylococcus aureus.

Mihai Ciustea,Sara Mootien,Adriana E Rosato,Oriana Perez,Pier Cirillo,Kacheong R Yeung,Michel Ledizet,Michael H Cynamon,Paul A Aristoff,Raymond A Koski,Paul A Kaplan,Karen G Anthony

Biochemical Pharmacology（2012）

Cited 19|Views11
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Abstract
L2-401 (4-[(4-fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione). A novel alanine racemase inhibitor.
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Key words
d-Alanine,Alanine racemase,Peptidoglycan,MRSA
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