Toxicity of a Modified PEG-Asparaginase-Based SMILE Regimen Is Comparable to L-Asparaginase-Based SMILE in a Non-Asian Population.

Amin Azem, Ryan Caddell,Rebecca Nelson,Leidy Isenalumhe,Sameh Gaballa,Julio Chavez,Celeste Bello,Javier Pinilla,Lubomir Sokol,Bijal Shah,Hayder Saeed

Journal of the National Comprehensive Cancer Network（2023）

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摘要

In a non-Asian population, the mSMILE regimen with PEG-asparaginase is a safe alternative to the L-asparaginase-based SMILE regimen. There is a comparable risk of hematological toxicity, and no treatment-related mortality was seen in our population.

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关键词

smile regimen,peg-asparaginase-based,l-asparaginase-based,non-asian

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