Improved Healing Of Extraperitoneal Intestinal Anastomoses In The Early Phase When Surrounded By Omentum
DIGESTIVE SURGERY(2000)
Abstract
Background: The extra-anatomical position of a cervical oesophagogastrostomy is a reason for impaired anastomotic healing, but transposition of the omentum that is covered with mesothelial cells may be a way to improve that. Method: This hypothesis was tested in a rat model. An end-to-end jejuno-jejunostomy was placed subcutaneously in group I In = 29), subcutaneously surrounded by omentum in group II In = 29) and intra-abdominally surrounded by omentum in group III (n = 20). After 3, 7 or 14 days, the rats were sacrificed and bursting pressure (BP) of the anastomosis or jejunum was measured and the hydroxyproline (HP) level was determined. Results: In group 15/29, in group II 2/29 and in group III 0/20 rats died following anastomotic leakage (nonsignificant) and were excluded from other measurements. BP was decreased after 3 days in group I (60 +/- 9 mm Hg) compared with group II (101 +/- 8 mm Hg) and group III (107 +/- 11 mm Hg) (p = 0.002). After 7 days, BP in groups I (122 +/- 10 mm Hg) and II (132 +/- 10 mm Hg) were lower as compared with group III (230 +/- 8 mm Hg) (p < 0.001). Differences in HP levels were not statistically significant between the groups after 3, 7 and 14 days. Conclusion: The healing of intestinal anastomoses in an extraperitoneal position is improved in the early phase only when surrounded by omentum. Copyright (C) 2000 S. Karger AG. Basel.
MoreTranslated text
Key words
omentum, intestinal anastomotic healing, extraperitoneal anastomoses
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined