The efficacy and tolerability of MK-0633, a 5-lipoxygenase inhibitor, in chronic asthma.

Yasmine S Wasfi,César Villarán,Celine Le Bailly de Tilleghem,Steven S Smugar,William D Hanley,Theodore F Reiss,Barbara A Knorr

Respiratory Medicine（2012）

引用 16|浏览4

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摘要

Leukotriene B4 (LTB4) is a potent inflammatory mediator in asthma, and is increased in more severe asthma. Targeting LTB4, in addition to cysteinyl leukotrienes, could be beneficial in asthma.

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关键词

Asthma,Leukotrienes,5-Lipoxygenase

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