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非酒精性脂肪性肝病大鼠解偶联蛋白2的表达及其与胰岛素抵抗的关系

Yuan-yuan CHEN,Li YUAN,Lian ZHU,Yin-hua CHEN,Bei ZHANG

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology（2008）

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Abstract
本研究通过高脂饮食喂养大鼠,观察大鼠肝内脂肪沉积情况,同时检测肝细胞解偶联蛋白2(UCP-2)和胰岛素信号分子胰岛素受体底物2(IRS-2)mRNA的表达,以探讨在非酒精性脂肪性肝病(NAFLD)发病中胰岛素抵抗与肝细胞U CP2表达的关联及其作用机制.
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Key words
fatty liver rats,insulin resistance,fatty liver,high-fat
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