Non-Mutagenicity Of Ytr 830 H, A Novel Beta-Lactamase Inhibitor

The Ames test indicated that a novel beta-lactamase inhibitor YTR 830 H, belonging to penicillanic acid sulfone was non-mutagenic for any of the tester strains of Salmonella typhimurium TA 98, TA 100 and TA 102. The test was performed both in the presence and absence of S9 activation mixtures which were prepared from the livers of Aroclor 1254-induced Syrian hamsters.