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Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.

Hashim Motiwala,Shivaji Kandre,Vishal Birar,Kishorkumar S Kadam,Atish Rodge,Ravindra D Jadhav,M Mahesh Kumar Reddy,Manoja K Brahma,Nitin J Deshmukh,Amol Dixit,Lalit Doshi,Amol Gupte,Ashok K Gangopadhyay,Ram A Vishwakarma,Shaila Srinivasan,Mamta Sharma,Kumar V S Nemmani,Rajiv Sharma

Bioorganic & Medicinal Chemistry Letters（2012）

Cited 15|Views8
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Abstract
The synthesis and biological evaluation of pyridine containing heteroaryl ureas as DGAT1 inhibitors have been reported.
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Key words
Diacylglycerol acyltransferase (DGAT),Obesity,Triglycerides,Fat tolerance test (FTT)
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