Investigation and management of fetomaternal alloimmune thrombocytopenia.

Australian and New Zealand Journal of Obstetrics and GynaecologyVolume 40, Issue 2 p. 176-179 Investigation and management of fetomaternal alloimmune thrombocytopenia Helen F Savoia, Corresponding Author Helen F Savoia Australian Red Cross Blood Service Victoria8 Division of Laboratory Services Women's and Children's Healthcare Network Royal Children's Hospital Flemington Road Parkville 3052 Victoria AustraliaSearch for more papers by this authorShaun P Brennecke, Shaun P Brennecke Department of Perinatal Medicine and University of Melbourne Department of Obstetrics and Gynaecology Royal Women's Hospital, AustraliaSearch for more papers by this authorRobert F Burrows, Robert F Burrows Maternal-Fetal Medicine Unit, Monash University, AustraliaSearch for more papers by this authorCathie F Hart, Cathie F Hart Victorian Transplantation and Immunogenetics Service, Southbank, VictoriaSearch for more papers by this authorRhonda Holdsworth, Rhonda Holdsworth Victorian Transplantation and Immunogenetics Service, Southbank, VictoriaSearch for more papers by this authorJack Metz, Jack Metz Department of Diagnostic Haematology, Royal Melbourne Hospital, Parkville, AustraliaSearch for more papers by this authorMichael Permezel, Michael Permezel University of Melbourne Department of Obstetrics and Gynaecology, Mercy Hospital for Women, East Melbourne, AustraliaSearch for more papers by this authorChristine Tippett, Christine Tippett Maternal-Fetal Medicine Unit, Monash University, AustraliaSearch for more papers by this authorEuan M Wallace, Euan M Wallace Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre, AustraliaSearch for more papers by this author Helen F Savoia, Corresponding Author Helen F Savoia Australian Red Cross Blood Service Victoria8 Division of Laboratory Services Women's and Children's Healthcare Network Royal Children's Hospital Flemington Road Parkville 3052 Victoria AustraliaSearch for more papers by this authorShaun P Brennecke, Shaun P Brennecke Department of Perinatal Medicine and University of Melbourne Department of Obstetrics and Gynaecology Royal Women's Hospital, AustraliaSearch for more papers by this authorRobert F Burrows, Robert F Burrows Maternal-Fetal Medicine Unit, Monash University, AustraliaSearch for more papers by this authorCathie F Hart, Cathie F Hart Victorian Transplantation and Immunogenetics Service, Southbank, VictoriaSearch for more papers by this authorRhonda Holdsworth, Rhonda Holdsworth Victorian Transplantation and Immunogenetics Service, Southbank, VictoriaSearch for more papers by this authorJack Metz, Jack Metz Department of Diagnostic Haematology, Royal Melbourne Hospital, Parkville, AustraliaSearch for more papers by this authorMichael Permezel, Michael Permezel University of Melbourne Department of Obstetrics and Gynaecology, Mercy Hospital for Women, East Melbourne, AustraliaSearch for more papers by this authorChristine Tippett, Christine Tippett Maternal-Fetal Medicine Unit, Monash University, AustraliaSearch for more papers by this authorEuan M Wallace, Euan M Wallace Department of Obstetrics and Gynaecology, Monash University, Monash Medical Centre, AustraliaSearch for more papers by this author First published: 13 February 2008 https://doi.org/10.1111/j.1479-828X.2000.tb01142.xCitations: 2AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Bussel JB. Skupsi DW, MacFarland JG. Fetal alloimmune throm bocytopenia: consensus and controversy. J Matern Fetal Med 1996; 5: 281– 292. 2 Bussel JB. Immune thrombocytopenia in pregnancy: autoim mune and alloimmune. J Reprod Immunol 1997; 3: 35– 61. 3 Paidas MJ, Berkowitz RL, Lynch L, et. al. Alloimmune thrombo cytopenia: fetal and neonatal losses related to cordocentesls Am J Obstet Gynecol 1995; 172: 475– 479. 4 Mueller Eckhardt C. Keifel V, Grubert A. et al. 348 cases of sus pected neonatal alloimmune thrombocytopenia Lancet 1989; 1 363– 366. 5 Boehlen F. Kaplan C. de Moerloose P Severe neonatal alloim mune thrombocytopenia due to aAnti HPA 3a Vox Sang 1998. 71 201 204. 6 Friedman JM. Aster RH. Neonatal alloimmune thrombocytopenic purpura and congenital porencephaly In two siblings associated with a “new” maternal antiplatelet antibody Blood 1985. 65. 1412– 1415. 7 Bussel JB. Zabusky MR. Berkowitz RI. MrFnrland JG Fetal alloimmune thrombocytopenia. N Engl J Med 1997. 337 22– 26. 8 Warkentln TE Smith JW The alloimmune thromcytopenic syndromes. Transfus Med Rev 1997; 11: 296– 307. 9 Blanchcttc VS., Chen I., de Fricdberit ZS., Hogan VA., Tnidel K., Decary F. Alloimmunization to the PIAI platelet antigen result of a prospective study, Br.J Haematol 1990. 74 209– 210). 10 Bessos H. Mlrza S. McGIII A. Williamson LM. Handfleld R. Murphy WG. A whole blood assay for platelet HPA1 (PI. AI1 phenotyplng applicable to large scale screening Br J Haematol 1998. 92 221– 225. 11 Von dem Borne AK. Verheugt FW. Oosterhof F. von Bissz K. de la Riviere AB. Engelfrlet CP A Simple Immunofluorescence test for the detection of platelet antibodies Br J Haematol 1978. 39 195– 207. 12 McMillan R. Tani P. Millard F. Berrhtold P. Renshaw I. Wods VL. Platelet associated and plasma anti glycoprotein auto-anti bodies in chronic ITP. Blood 1987: 70: 1040 1045. 13 Newman PJ. Derbes RS. Aster RH. The human platelet alloantigens. P1A1 and P1A2. are associated with a Ieucine33 pmltne. amino acid polymorphism in membrane glycoprotein I. and are distinguishable by DNA typing. J Clin Invest 1989: 83 1778– 1781. 14 McFarland JG. Aster RH. Bussel JB. Gianopoulos JG. Derbes RS. Newman PJ Prenatal diagnosis of neonatal alloimmune thrombocytopenia using allele-specific oligonucleotide probes. Blood 1991; 78: 2276– 2282. 15 Reznikoff-Etievent MF. Management of alloimmune neonatal and antenatal thrombocytopenia. Vox Sang 1988; 5: 193– 201. 16 Bussel JB, Tanli S, Peterson H. Favorable neurologic outcome in 7 cases of perinatal intracranial hemorrhage due to immune thrombocytopenia. Am J Pediatr Hematol Oncol 1991; 13: 156– 159. 17 Bussel JB. Neonatal alloimmune thrombocytopenia(NArT): a prospective case accumulation study. Pediatr Res 1968; 23: 337a. 18 Murphy MF, Pullon HW, Metcalfe P, et. al. Management of fetal alloimmune thrombocytopenia by weekly in utero platelet transfusions. Vox Sang 1990; 58: 45– 49. 19 Letsky EA. Greaves M. Guidelines on the investigation and management of thrombocytopenia in pregnancy and neonatal alloimmune thrombocytopenia. Maternal and Neonatal Haemostasis Working Party of the Haemostasis and Thrombosis Task Force of the British Society for Haematology. Br J Haematol 1996; 95: 21– 26. 20 Giovangrandi Y. Daffos F. Kaplan C. Forestier F, Mac Aleese J, Moirot M. Very early intracranial haemorrhage in alloimmune fetal thrombocytopenia. Lancet 1990; 336: 310. 21 Dickinson JE, Marshall LR, Phillips JM, Barr AL. Antenatal diagnosis and management of fetomatemal alloimmune thrombocytopenia. Am J Perinatol 1995; 12: 333– 335. 22 Kaplan C, Murphy MF, Kroll H, Waters AH. Feto-maternal alloimmune thrombocytopenia: antenatal therapy with IvIgG and steroids - more questions than answers. European Working Group on FMAIT. Br J Haematol 1998; 100: 62– 65. 23 Lynch L, Bussel JB, McFarland JG, Chitkara U, Berkowitz RL. Antenatal treatment of alloimmune thrombocytopenia. Obstet Gynecol 1992; 80: 67– 71. 24 Porcelijn L, Kanhai HH. Fetal thrombocytopenia. Curr Opin Obstet Gynecol 1998; 10: 117– 122. 25 Kroll H, Kiefel V, Giers G, et. al. Maternal intravenous immunoglobulin treatment does not prevent intracranial haemorrhage in fetal alloimmune thrombocytopenia. Transfus Med 1994; 4: 293– 296. 28 Bussel JB, Berkowitz RL, Lynch L, et. al. Antenatal management of alloimmune thrombocytopenia with intravenous gamma-globulin: a randomised trial of the addition of low dose steroid to intravenous gamma-globulin. Am J Obstet Gynecol 1996; 174: 1414– 1423. Citing Literature Volume40, Issue2May 2000Pages 176-179 ReferencesRelatedInformation