An infant with hypereosinophilic syndrome and heart failure markedly responded to prednisolone: serial changes of left ventricular wall thickening and left ventricular diastolic dysfunction observed by echocardiography

Summary We encountered an infant with congestive heart failure due to idiopathic hypereosinophilic syndrome. The patient showed marked thickening of the left ventricular wall and left ventricular diastolic dysfunction, both of which, shortly after prednisolone therapy, markedly improved together with improvement of the congestive heart failure and hypereosinophilia. Observation of pulmonary venous flow patterns detected by pulsed Doppler echocardiography may be useful for evaluation of left ventricular diastolic function.