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Detection of Viral Nucleoprotein Binding to Anti-Influenza Aptamers Via SERS

Pierre Negri,Andreas Kage,Andreas Nitsche,Dieter Naumann,Richard A. Dluhy

Chemical Communications（2011）

Cited 47|Views1
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Abstract
A highly sensitive surface-enhanced Raman (SERS)-based method for detection of influenza viral nucleoproteins is described. The intrinsic SERS spectrum of the aptamer-nucleoprotein complex provides direct evidence of binding between a polyvalent anti-influenza aptamer and the nucleoproteins of three influenza strains.
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Infectious Disease Detection
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