[Intracranial ependymomas in adult patients. Diagnosis and histological prognostic factors].

D Figarella-Branger,P Metellus,M Barrié,A Maues de Paula, C Fernandez,M Polivka,A Vital,F Labrousse, J-M Vignaud,A Laquerrière, M-C Rousselet,C Lacroix, S Saikali,F Chapon, M-F Gontier,F Chrétien, P Babin,V Rigau, F Vandenbos,M Peoc'h, M Kujas,O Chinot,J Gouvernet,R Giorgi,J Guyotat,A Jouvet

Neuro-Chirurgie（2007）

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Abstract

Among the 121 ependymomas, 88 were grade II (47 classic, 17 cellular, 2 papillar, 6 clear cells and 16 tanicytic) and 33 grade III. WHO grading, occurrence of microvascular proliferation, necrosis, nuclear atypia and high proliferative index were correlated with both OS and DFS. Moreover, quantification of certain parameters enabled a reproducible grading system correlated with both OS and DFS.

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