DISTAL OBLITERATING ARTERIOPATHY OF THE LOWER-LIMBS IN A SYSTEMIC-DISEASE - TREATMENT WITH NORMOVOLEMIC HEMODILUTION - REPORT OF ONE CASE

The authors report on a 31 year old man with a generalised illness consisting of: buccal aphtous ulcers, distal arteriopathy, multiform cutaneous lesions (necrotising vasculitis, folliculitis, nodules), hypersensitivity at the site of puncture, Raynaud's syndrome and superficial venous thromboses. After the failure of various therapies (calcium heparin, ticlopidine, colchicine, corticoids, immunostimulants), the patient was successfully treated by normovolemic haemodilution on 20 occasions, optaining each time healing of the skin lesions within 2 to 4 weeks.