CFTR three-dimensional structure.
CYSTIC FIBROSIS: DIAGNOSIS AND PROTOCOLS, VOL I: APPROACHES TO STUDY AND CORRECT CFTR DEFECTS（2011）
Abstract
CFTR is a member of the ATP-binding cassette family of membrane proteins. This is one of the best characterised membrane protein families in terms of structure and function. CFTR operates as an ion channel, unlike nearly all other family members which are active transporters. Here, we discuss methods that have allowed such data to be obtained for CFTR.
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Key words
CFTR,cystic fibrosis,structure,ion channel,membrane protein,electron microscopy,electron crystallography
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