Screening Of Peptides Which Suppress The Proliferation Of Transformed Cells

T Hiwasa, C Soeda, S Takanohashi, H Kobayashi, A Suzuki, T Ueyama, Y Ike

INTERNATIONAL JOURNAL OF ONCOLOGY(1996)

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摘要
We have carried out three rounds of screening tests using 239 synthetic tripeptides for the growth-inhibitory activity toward tumor cells and found that those having amino acid sequences of Pro-Thr-Trp or Glu-Arg-Pro effectively inhibit proliferation of transformed cells. These peptides could be the fundamental structures of new types of anticancer drugs.
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关键词
anticancer drug, MTT, peptide
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