Tandem stem cell rescue as consolidation therapy for high-risk neuroblastoma.

Muna Qayed, Kuang-Yueh Chiang,Richard Ricketts,Adina Alazraki,Ali Tahvildari,Ann Haight,Brad George,Natia Esiashvili,Howard M Katzenstein

PEDIATRIC BLOOD & CANCER（2012）

引用 17|浏览8

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摘要

Background Despite aggressive treatment for high-risk neuroblastoma (NB), event-free survival (EFS) remains <40%. In single arm studies, intensifying therapy with high-dose chemotherapy and tandem autologous stem cell rescue (HDC/SCR) improved outcome. We retrospectively describe our institutional experience in using HDC/SCR for patients with high-risk NB, focusing on outcome and acute toxicities.

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关键词

high-risk neuroblastoma,stem cell rescue,tandem transplant

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