Typhoid fever among hospitalized febrile children in Siem Reap, Cambodia.

Lalith P M Wijedoru,Varun Kumar,Ngoun Chanpheaktra,Kheng Chheng,Henk L Smits,Rob Pastoor,Tran Vu Thieu Nga,Stephen Baker,Vanaporn Wuthiekanun,Sharon J Peacock,Hor Putchhat,Christopher M Parry

JOURNAL OF TROPICAL PEDIATRICS（2012）

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摘要

Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

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关键词

typhoid fever,nucleic acid amplification test,rapid diagnostic test,blood culture,children

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