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A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment

Modern rheumatology / the Japan Rheumatism Association(2011)

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摘要
A female patient with rheumatoid arthritis (RA) suffered from Mycobacterium avium ( M. avium ) infection during tocilizumab treatment. Tocilizumab was discontinued and she was treated with a recommended chemotherapy, resulting in improvement of M. avium . Tocilizumab retreatment did not aggravate M. avium infection, and radiographic abnormalities improved over 1 year after cessation of the recommended therapy. Tocilizumab may be one candidate for intractable RA patients with M. avium if any biologic is required.
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关键词
Anti-IL-6 receptor antibody,Biologics,IL-6,MAC,TNFα
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