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Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. II. Structure determination of leuhistin.

S Yoshida,H Naganawa,T Aoyagi,T Takeuchi, Y Takeuchi,Y Kodama

The Journal of antibiotics（1991）

Cited 38|Views2
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Abstract
Leuhistin, a new inhibitor of aminopeptidase M, has been isolated from the culture broth of Bacillus laterosporus BMI156-14F1. The structure of leuhistin was determined by NMR studies. X-Ray and chemical analysis confirmed the absolute structure to be (2R,3S)-3-amino-2-hydroxy-2-(1H-imidazol-4-ylmethyl)-5-methylhe xanoic acid.
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leuhistin,new inhibitor
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