Acute erythroleukemia with t(3;5) accompanied by hepatocellular carcinoma.

H Nakagawa,S Tanaka, T Takashima, Y Shizumi,H Nishigaki, S Horiike, M Taniwaki, S Misawa,K Kashima, T Hironaka

International journal of hematology(1991)

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Abstract
A female patient in whom acute nonlymphocytic leukemia (ANLL, FAB-M6) developed during treatment of hepatocellular carcinoma (HCC) is described. Two years after partial hepatectomy and subsequent chemotherapy, leukemia developed following a 2 month preleukemic stage. Chromosomal analysis revealed an abnormal karyotype, 46,XX,-5, + der(5)t(3;5)(q25;q31). The balanced translocation t(3;5) has been observed in all types of ANLL and MDS except for ANLL M3 subtype. We summarize patients with ANLL M6 and t(3;5).
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Key words
ANLL, ERYTHROLEUKEMIA, MYELODYSPLASTIC SYNDROME, T(3-5), HEPATOCELLULAR CARCINOMA
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