Four new polyoxygenated gorgosterols from the gorgonian Isis hippuris.

Mohammad Helal Uddin,Novriyandi Hanif,Agus Trianto,Yutaka Agarie,Tatsuo Higa,Junichi Tanaka

NATURAL PRODUCT RESEARCH（2011）

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摘要

Four new polyoxygenated steroids (1-4) together with four known ones (5-8) have been isolated from the gorgonian Isis hippuris. The structures of the new compounds have been elucidated by spectroscopic analysis and chemical conversion. All of the new steroids showed moderate cytotoxicity against cultured NBT-T2 cells.

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关键词

polyoxygenated steroids,gorgosterol,NBT-T2,cytotoxicity

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