Chemotherapeutic management of small bowel adenocarcinoma associated with Crohn's disease.

H W Bruckner,V R Hrehorovich, H S Sawhney, S I Meeus, A M Coopeman

JOURNAL OF CHEMOTHERAPY（2013）

Cited 10|Views4

No score

Abstract

Four patients with metastatic primary small bowel adenocarcinoma associated with Crohn's disease were successfully treated with low dose combination chemotherapy consisting of 5-fluorouracil, leucovorin and irinotecan with or without gemcitabine. Benefits included prolonged survival, objective responses, response of resistant tumors, downstaging, and a successful secondary complete resection (Ro) with a durable remission.

Translated text

Key words

small bowel adenocarcinoma,Crohn's disease,chemotherapy,irinotecan,Gemcitabine,resistance,fluorouracil,resection,downstaging,anastomotic recurrence,salvage (secondary) chemotherapy

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined