Changes in alpha-B-crystalline in heart transplants]

L I Kovalev,E S Ershova, L I Obel'chuk,D A Tsomartova,P Z Khasigov, V V Severin, E I Riaboshtanova, I M Il'inskiĭ,S S Shishkin

Biulleten' eksperimental'noĭ biologii i meditsiny（1998）

Cited 23|Views2

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Abstract

Plasma level of lipid-standardized vitamin E is decreased, while the concentration of inflammatory transmitters C3a(desArg) and C5a(desArg) is elevated in heterozygous familial hypercholesterolemia caused by apoB,E-receptor deficiency. Leukocytes isolated from these patients exhibit enhanced spontaneous aggregation of superoxide anion generation and are resistant to activation with exogenous platelet activation factor (10−6 M).

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Key words

heart transplants,alpha-b-crystalline

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