Survival of pulmonary cancer patients treated surgically.

Prilozi / Makedonska akademija na naukite i umetnostite, Oddelenie za biološki i medicinski nauki = Contributions / Macedonian Academy of Sciences and Arts, Section of Biological and Medical Sciences(2010)

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Abstract
(Full text is available at http://www.manu.edu.mk/prilozi). The aim of the study is to investigate the survival of patients treated surgically for lung cancer. 151cases treated during the years 2000-03 are reviewed. The average age was 56.6 ± 9.9 years (from 19 to 83 years old). The histological type was: 80 (53%) Squamous-cell carcinoma, 27 (17.9%) adenocarcinoma, 10 (6.6%) bronchioalveolar carcinoma, 5 (3.3%) small-cell carcinoma, and others - 29 (19.2%). The post-surgical stage was often advanced; 92 (63%) of the patients were at stage IIIA. With 5 (3.3% of total operated cases) of the patients had limited disease of SCLC. Most of the patients had lobectomy (64.9%) and pneumonectomy (16.6%) Performed. Neoadjuvant treatment was carried out on 37 (24.5%) of the patients. Only half of the patients were alive after 1 year, and 11.9% after 2 years of the postoperative period. Survival was highly significantly better in patients with an early stage of the disease. Survival resulted decreasingly with the extent of the surgical intervention; lower survival resulted in the patients treated with pneumonectomy, but this was not statistically significant. Significantly better results of survival were seen in correlation with higher values of pre-surgical FEV1. There are significant differences in survival (p < 0.05) in relation to diagnosis, group-age, histology, and highly significant differences (p < 0.01) regarding definition N, M, stage of disease, FEV1. There were no significant differences in the survival of patients according to sex, type of intervention, site of intervention, FVC, definition T. Key words: Pulmonary carcinoma, surgery, survival.
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