The Hla-B83:01 Allele Is Generated By A Gene Conversion Event Including Whole Of Exon 2 And Partial Introns 1 And 2 Between B44 And B*56 Alleles

I Cervera,M A Herraiz,J A Vidart,J Peñaloza,J Martinez-Laso

INTERNATIONAL JOURNAL OF IMMUNOGENETICS（2011）

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摘要

P>Several studies have indicated the gene conversion as the most important mechanism about the MHC polymorphism generation when intron sequences are studied. The data obtained confirm that the B*83:01 allele is generated by gene conversion event including exon 2 and partial intron 1 and 2 between B*44 and B*56 alleles.

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generated conversion event,partial introns

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The Hla-B*83:01 Allele Is Generated By A Gene Conversion Event Including Whole Of Exon 2 And Partial Introns 1 And 2 Between B*44 And B*56 Alleles

The Hla-B83:01 Allele Is Generated By A Gene Conversion Event Including Whole Of Exon 2 And Partial Introns 1 And 2 Between B44 And B*56 Alleles