The intergenic spacer region of the ribosomal RNA gene of Penicillium marneffei shows almost no DNA sequence diversity.

Nanthawan Mekha,Takashi Sugita,Koichi Makimura,Natteewan Poonwan,Pathom Sawanpanyalert,Reiko Ikeda,Akemi Nishikawa

Microbiology and immunology（2010）

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摘要

The fungus Penicillium marneffei causes fatal systemic infections and is endemic in many parts of South-East Asia, especially Thailand. The intergenic spacer (IGS) region, the most variable region of rRNA genes, was found to be highly conserved among 58 P. marneffei strains. IGS analysis might not be suitable for molecular epidemiological analysis of P. marneffei infections.

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关键词

intergenic spacer region,intraspecies diversity,Penicillium marneffei

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