Novel 1,5-benzodiazepines as CCK-B ligands. Effect of aryl-carbamic substituents at the C-3 position together with halogen substitution on the benzo-fused ring.

M. Elvira Tranquillini,Paolo G. Cassarà,Mauro Corsi,Giovanni Curotto,Daniele Donati,Gabriella Finizia,Giorgio Pentassuglia,Stefano Polinelli,Giorgio Tarzia,Antonella Ursini,Franciscus T. M. van Amsterdam

ARCHIV DER PHARMAZIE（1997）

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摘要

The synthesis and biological evaluation as potential CCK-B receptor ligands of a number of 1-isopentyl-3-aryloxycarbamoyl-5-aryl-1,5-benzodiazepines substituted with halogen atoms on the benzo-fused ring is here briefly discussed.

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关键词

cholecystokinin A (CCK-A),cholecystokinin B (CCK-B),1,5-benzodiazepines

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